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When it comes to weight loss, some research shows that tirzepatide (the active ingredient in Zepbound) is more effective and may help people lose 15% or more of their body weight

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Whitney Linsenmeyer, PhD, RD, Assistant Professor of Nutrition and Dietetics The Frustrating Reality of Yo-Yo Dieting Weight regain is quite common, with one study suggesting less than 6% of people sustain weight loss 15 years after undergoing a weight loss program