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A July 2024 Harvard study found diabetes patients prescribed semaglutide were over four times likely to develop NAION, while those prescribed it for weight loss were over seven times likely to develop this condition

Hormonal fluctuations during weight loss can be complex and variable

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Nevertheless, increasing evidence in this field emphasizes the importance of the gut microbiota in the maintenance of kidney and brain health, implying that further targeting of the gut microbiota via various means holds potential for the improvement of such chronic disease conditions as CKD and neurodegenerative disorders