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In vitro, C16-carnitine has been found to activate specific subsets of neurons in the dorsal root ganglia (DRGs) of muscles that play a key role in sensing muscle fatigue or exertion and are involved in transmitting these sensory signals to the CNS, indicating that C16-carnitine acts as a signaling molecule for muscle afferent nerves [281]
This connection to iron homeostasis may have broader implications for anemia and age-related changes in blood cell production
Evidence type: Human RCT | Observational | Animal
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