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Thus the use of AZA is now limited to patients who are unable to tolerate mycophenolate or sirolimus, or when pregnancy is planned since mycophenolate and sirolimus have significant teratogenic potential and should be avoided
Statistical significance was determined using an unpaired two-sided Students t tests or one-way ANOVA
368 Since GLP-1R is expressed in thyroid C cells and GLP-1 directly stimulates the secretion of calcitonin, which is a potent inhibitor of bone resorption in osteoclasts, GLP-1 may contribute to the nutrient-mediated reduction in bone resorption
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