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Contraindications GLP-1 is not recommended if you have a family history of medullary thyroid cancer or a history of pancreatitis
This means you flush out essential nutrients, like vitamin B12, through excessive urination
Meta-analyses pooling trial data indicated statistically significant differences favoring tirzepatide for percent weight loss, but semaglutide remained highly effective and better tolerated by some participants, notably in community practice
Whilst B12 plays a vital role in energy metabolism, supplementation does not promote fat loss in individuals with normal B12 levels
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