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Upon binding to the receptor, GLP-1 and its analogs also initiate a variety of additional anti-diabetic effects, including, but not limited to, reduction in gastric emptying, increase in satiety and inhibition of food motivated behavior, replenishment of insulin stores, as well as cytoprotective and anti-inflammatory actions on -cells (29)

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For example, in a phase II trial, liver transplant patients given low-dose nitrite had lower AST release and better bile production