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Since apoptosis is defined by the NCCD as a caspase-dependent RCD [4], and considering the fact that eryptotic pathways dont culminate in activation of caspases [84], it has become clear that eryptosis is guided and executed alternatively
At the moment, it is not clear whether iron overload induces eryptosis in erythrocytes or might trigger a unique RCD similar to ferroptosis of nucleated cells
Among them, an important type is the vacuolar ATPase (v-ATPase) which is constituted by subunits such as ATP6V1B1, ATPV1B2 and ATP6V0A4
Neuroblastoma SH-SY5Y had a complete opposite behavior, being sensitive to hydrogen peroxide, but resistant to diamide
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