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Proc Natl Acad Sci U S A 98: 14126-14131

To minimize these events, Sean Wharton, MD, director of the Wharton Medical Clinic in Toronto, and colleagues suggest the three Es: E ducation and explanation E scalation to an appropriate dose E ffective management of GI side effects. Patients should be counseled on means to decrease adverse event risk such as reducing meal size

In studies, Mounjaro helped people lose 12 to 15 pounds on a 5-mg weekly dose, between 15 and 21 pounds on a 10-mg weekly dose, and between 17 and 25 pounds on a 15-mg weekly dose

If you experience sustained energy improvement and the cost-benefit ratio is favorable, continuing long-term is reasonable