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Mutations in mitochondrial DNA (mtDNA), commonly detected across cancers such as renal oncocytoma, gastric adenocarcinoma, renal cell carcinoma, bladder cancer, ovarian cancer, thyroid cancer, and pancreatic cancer, 208,209,210,211,212,213,214,215 can disrupt OXPHOS, enhance ROS production, and promote tumorigenesis
[47] See Law.com, supra note 41
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95% confidence interval (CI) 0.630.88
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