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But I have plenty of others who have used the spray for years with no issues

When patients are on multiple oral agents with suboptimal control and significant treatment burden, transitioning to tirzepatide monotherapy or simplified combination therapy may improve both efficacy and adherence

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Under carefully engineered pharmacologic conditions, it may become a complementary metabolic signal that helps transform incretin therapy from appetite suppression alone into a more comprehensive strategy targeting appetite, substrate oxidation, hepatic metabolism, and energy expenditure