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They may be experiencing anaphylaxis, which is a severe allergic reaction
In diet-induced obese mice, 30 days of once-daily subcutaneous dosing limited fat-mass gain to 1.3 g versus 4.7 g in controls, but only at 32 mg/kg/day
In the clinical trial, participants who started at higher initial doses experienced significantly more gastrointestinal side effects than those who began at 2 mg
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