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At the highest dose of 12 mg retatrutide, the average weight loss after 48 weeks was 24.2% with reduction up to 30% from the baseline weight in 25% of participants
Protein concentration was measured using the Pierce BCA Protein Assay
Detection of cellular thiols was done using monobromobimane (MBB, ThermoFisher M1378) added 10 min before acquisition at 50 M
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