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A layered regimen can address these pressures simultaneously: MI uncouples insulin-androgen crosstalk, vitamin D recalibrates inflammatory and steroidogenic set-points, and melatonin restores mitochondrial resilience and temporal order

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Under dark conditions at 25 C, the absorbance of the nitro-2-thiobenzoate anion (TNB-) at 412 nm remained consistent for more than three hours

Micro-CT analysis showed that some Nrf2 KO OA mice displayed relatively higher amount of subchondral trabecular bones (Fig