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Melanotan I, being more selective for MC1R, remains more skin focused in its pharmacology and is typically administered as a slow-release subcutaneous implant in its approved medical form, smoothing out plasma concentrations and reducing peaks that can amplify side effects
Buse JB et al
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GLP-1R is widely expressed in the whole body, mainly in the lungs, kidneys, heart, adipose tissue, and the central and peripheral nervous systems [3]
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