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4.3
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Description

Joint pain: Chronic stiffness that doesn't resolve with rest can be a sign of poor connective tissue repair

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The evidence for this is provided by evaluating the liver function biomarkers, CYP2E1 gene expression, iron overload, oxidative stress, SIRT-1 expression and hepatic architecture damage associated with APAP overdose

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McFarlan et al., 1992)

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Who Should Avoid: Pregnant or breastfeeding women

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