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Interestingly, the SURMOUNT-5 trial found that gastrointestinal adverse events causing treatment discontinuation occurred in 5.6% of semaglutide users compared to only 2.7% of tirzepatide users
Oral NSAIDs should be used cautiously and only after discussion with your GP, particularly if you have cardiovascular disease, renal impairment, or gastrointestinal problems
These observations qualified the HepG2 model to study the mechanisms described herein
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