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Limited weight loss benefit
According to current studies, the molecular pathways involved in GLP-1RAs impact on RGCs rescue can be categorized into two groups (Figure 2)
An important role of folic acid is the formation of methionine from homocysteine using vitamin B12 as a cofactor
Overall, sulforaphanes safety profile appears favorable, with manageable adverse events supporting its use as a treatment adjunct, pending further long-term safety data
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