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Silverstein said he decided to investigate the over-prescribing of B12 shots, because "as an internal medicine resident, I have seen many patients come into the emergency department, and they were getting B12 injections without having a really good reason for it." His study could not determine why family physicians were prescribing it inappropriately including whether it was initiated by the doctor or at the request of the patient

If youre correcting a deficiency, you might start with weekly injections and shift to monthly maintenance

Clinicians who do prescribe AOD-9604 in this age group under a documented informed-consent framework should, at minimum, measure standing height and sitting height every 3 months, track height velocity against population norms, assess Tanner stage at each visit, and obtain fasting IGF-1 and IGFBP-3 levels at baseline and every 3 months [18]