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Heart-rate changes are seen across the incretin class, but the glucagon component may contribute here, and the long-term clinical significance is precisely the kind of question phase 3 cardiovascular follow-up is meant to resolve

Glutathione and Breastfeeding As our bodies transition from pregnancy to breastfeeding, we may wonder about the safety of continuing to take supplements like glutathione

Dietary interventions The study implemented an IF regimen for the intervention group, allowing only non-caloric beverages during a 16-hour fasting period and unrestricted eating for 8 h

Clinical studies We split this section between studies of GLP-1RAs in people with mood disorders and studies of mood symptoms in patients with other medical conditions taking GLP-1RAs (Tables 4 and 5, and Extended Data Tables 5 and 6)