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Moreover, NO seems to be the only mediator of cell proliferation arrest through the ERK1/2-p53 signaling pathway ( FIGURE 1 Next to this evidence, in our laboratory it has been demonstrated that GSH depletion modulates the peroxisome proliferator-activated receptor gamma, co-activator 1 alpha (PGC-1) expression and its downstream metabolic pathway in neuronal and skeletal muscle cells ( Figure 1 )
"People have tried to change overall glutathione levels, but now we have a way to change it in mitochondria without impacting other parts of the cell
2001 May;24(5):875-80
Biomed Res Int 2015:627471 Erboga M, Kanter M, Aktas C, Bozdemir Donmez Y, Fidanol Erboga Z, Aktas E, Gurel A (2016) Anti-apoptotic and anti-oxidant effects of caffeic acid phenethyl ester on cadmium-induced testicular toxicity in rats
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