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This can look like insomnia, because you wake up over and over without remembering it
Serious adverse effects such as severe abdominal pain (which may indicate pancreatitis), persistent vomiting leading to dehydration, or signs of thyroid tumors (neck mass, difficulty swallowing, persistent hoarseness) require immediate medical attention
Therefore, findings are inconsistent for metformin response in this gene (Christensen et al., 2011
In prespecified subgroup analyses of the pooled evidence, effects appeared more favorable in trials enrolling older adults (60 years
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