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In a longitudinal cohort study (n = 6404) the relationship between adverse childhood events (ACEs), flavonoid intake and depressive symptoms in adulthood was investigated
Gene ontology analysis of the PFC revealed that prenatal stress robustly enriched metabolic, mitochondrial, and transporter-related gene programs, whereas enrichment in the combined THC/stress group was more restricted, involving a narrower subset of bioenergetic and respiratory-chain-associated genes
The main exception is bupropion, which tends to be weight-favourable, and is one of the two ingredients in Contrave
K.DrevetJ
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