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Plotting and mapping the changes in CSPs when bound with 6 M 1907 compared to DMSO control demonstrated that 1907 was able to induce CSP differences primarily in helix 23, specifically residues: M953, K955, E956, L959, R962, T963, L990, L994, G995 (Fig
They possess potent anti-inflammatory and immunosuppressive properties, which can effectively regulate the activity of SLE and relieve associated symptoms (105, 106)
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