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The label is very specific about how to take it: swallow the tablet whole on an empty stomach when you first wake up, with no more than 4 ounces of plain water, then wait at least 30 minutes before any food, other beverages, or other oral medications
Article CAS Google Scholar Download references Acknowledgements The cryo-EM data were collected at Cryo-Electron Microscopy Research Center, Shanghai Institute of Material Medica
But most over-the-counter B12 supplements contain far more in the range of 500 to 1,000 micrograms, she says, adding, That sounds pretty excessive, but its actually intentional since oral B12 absorption is inefficient
Grunvald E, et al
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