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Most patients can begin tirzepatide approximately seven days after their last semaglutide dose, typically starting at a low introductory dose of 2.5mg to ensure the body adjusts to the new dual-hormone mechanism
Leppluoto J, Westerlund T, Huttunen P, Oksa J, Smolander J, Dugu B, Mikkelsson M
PAT was found to reduce the cytokine secretion of IFN- and IL-4 by human macrophages [136] and of IL-4, IL-13, IFN-, and IL-10 by human peripheral blood mononuclear cells and human T cells [137]
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