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Reducing the amount of subcutaneous fat may require changes in lifestyle, diet, and exercise
A newly observed adverse event in Phase 2 and 3 investigational trials dysesthesia (abnormal skin sensations) was reported in approximately 20% of participants at the highest doses and has not been a notable feature of mono- or dual-agonist predecessors, suggesting this may be GCGR-mediated
SURMOUNT-MMO (tirzepatide).
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