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Spinocerebellar ataxia type 2 Spinocerebellar ataxia type 2a genetic neurodegenerative disorder due to a CAG repeat expansion mutation in the ATXN2 gene coding for the protein ataxin-2 63 has been associated to oxidative stress, in particular due to alterations in the enzymatic activity of antioxidant enzymes including GSTs 64

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We focused particularly on Groups 3 and 4, which showed increased expression in PostNAC samples compared with PreNAC samples in the recurrence group, and conversely on Groups 7 and 8, which showed decreased expression in PostNAC samples