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This increase of FFA in the liver and circulation results in hypertriglyceridemia, pronounced in the postprandial period, and fasting dyslipidemia leading to insulin resistance, obesity, and unfavorable changes to the cardiometabolic profile [10, 11]
SUMMARY Evaluation of drug delivery systems for GLP-1 receptor agonists from injectable to advanced oral, buccal, transdermal, and intranasal formulations has resulted in significant milestones in the treatment of obesity and type 2 diabetes
Beyond appetite suppression, they modulate adipose-derived inflammatory factors, leading to reduced leptin resistance and lower levels of C-reactive protein (CRP)
Thats why responsible prescribing as Scott highlights requires screening for disordered eating, nutritional compromise, and vulnerability factors
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