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Additionally, further investigations are underway to explore potential additional uses of tirzepatide in the clinical management of other cardiometabolic conditions associated with obesity, including heart failure and non-alcoholic (or metabolic-dysfunction associated) steatohepatitis (NASH/MASH)
administration of the experimental compounds (MK-801, GLP-1, GLP-1MK-801 (all at doses of 100 nmol kg 1 ), semaglutide (10 nmol kg 1 ) or isotonic saline as vehicle)
Canning S, Waterman M, Orsi N, Ayres J, Simpson N, Dye L
Physiol., 110 (3):774-780
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