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Concurrently, impaired function of regulatory receptors, such as triggering receptor expressed on myeloid cells 2 (TREM2), reduces phagocytic clearance and attenuates anti-inflammatory signaling, thereby impairing endogenous resolution pathways (Ajoolabady et al., 2025)
Enrichment analysis of GO and KEGG revealed that SMC contraction, extracellular matrix regulation, inflammatory signaling pathways, and cell death were highlighted (Supplemental Figure S1C)
Glutathione is not a one-session treatment
These cells serve as sentinels of hepatic innate and adaptive immunity, and their distribution altering during aging (54)
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