Clinical Evidence From Semaglutide Weight Loss Trials The SUSTAIN-6 cardiovascular outcomes trial, which followed over 3,000 patients with type 2 diabetes, documented systolic blood pressure reductions averaging 3.5 mmHg in the semaglutide group compared to placebo
Safety Profile and Side Effects Common Side Effects : Gastrointestinal symptoms nausea, diarrhoea, vomiting, and constipation are the most frequently reported
The agency also issued multiple waves of warning letters (dozens in total) to telehealth companies, citing false or misleading claims that suggested compounded products were equivalent to FDA-approved drugs in safety, efficacy, or quality.
The most common symptoms, which are mild and temporary, include abdominal pain, loose stools, and increased flatulence (mostly associated with oral supplementation)