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Dihexa is generally well tolerated when used under medical supervision, and most people report few side effects
Interactions with common perioperative and orthopedic drugs NSAIDs, corticosteroids, and anesthetic agents are uncharacterized, which matters precisely because orthopedic patients are frequently on those medications
Patients should maintain adequate hydration and monitor their symptoms
As the American Society of Health-System Pharmacists puts it in its guide to assigning beyond-use dates: "Ultimately the assigned BUD should default to the more conservative dating after an assessment of sterility and stability." Stability is the peptide chemistry
