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449 Notably, a dosage of 10 mg/kg/day of methazolamide significantly improved these parameters, exhibiting similar efficacy to 30 mg/kg/day of acetazolamide
Correlated with these biochemical changes, a significant reduction of 19% and 68% was observed in the root lengths of the seedlings showing a concomitant 13% and 46% decrease in total folate level, respectively (Fig
N Engl J Med 375:18341844 Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N, Maggioni AP, Marso SP, hman P, Pagidipati NJ, Poulter N, Ramachandran A, Zinman B, Hernandez AF (2017) EXSCEL Study Group