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Comorbidities CVS is probably not the result of a single pathogenetic mechanism, rather the common final clinical picture (cyclical emesis attacks) of different physiopathological pathways, with different threshold, and many triggers can be able to elicit it (79)
Furthermore, as mentioned, POMC is a precursor for -MSH, which helps control appetite
Medical trials for specific uses have increased dosage to three or four times that, but this is under medical supervision and using different formats
Appl Water Sci 15 , 146 (2025)
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