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Patients with high-sensitivity GLP1R variants benefit from even slower titration schedules or microdose protocols, while those with lower sensitivity may tolerate faster escalation
10.1097/MCO.0b013e328302f414 82 Mauvais-JarvisF.CleggD
Researchers with type 2 diabetes following a retatrutide dose schedule need to monitor blood glucose closely during each escalation step, as the improved insulin sensitivity can cause hypoglycemia if diabetes medications are not adjusted accordingly
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