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Studies discover that metastasis is not an autonomous program but is highly complex and multistep event, which occurs due to high mutational burden in cancerous cells and crosstalk between malignant cells and their non-malignant counterparts [31]

Molecular pathways: mitochondrial reprogramming in tumor progression and therapy

Ranke MB, Savage MO, Chatelain PG, Preece MA, Rosenfeld RG, Wilton P