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BPC-157 modulates inflammatory pathways through EGR-1 transcription factor regulation, helping resolve the inflammatory state that perpetuates tissue dysfunction
A person with normal overall body weight but elevated visceral fat (sometimes called TOFI: Thin Outside, Fat Inside) may have worse metabolic health markers than someone who is visibly overweight but carries their fat subcutaneously
Other groups who may benefit include: Patients following gastric surgery (gastrectomy, bariatric procedures) where intrinsic factor production or absorption sites are compromised Individuals with malabsorption disorders such as Crohn's disease, coeliac disease, or chronic pancreatitis Strict vegans and vegetarians with dietary insufficiency, though oral supplementation is usually tried first Elderly patients with atrophic gastritis or reduced gastric acid production Patients on long-term metformin or proton pump inhibitors, which can impair B12 absorption [6] [8] Individuals with nitrous oxide exposure (recreational or medical), which can cause functional B12 deficiency Diagnosis typically involves serum B12 measurement, with levels below approximately 148 pmol/L (though thresholds vary between laboratories) generally indicating deficiency
This support enables you to keep the weight off even if you eventually stop taking the medication
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