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This baseline data guides your dosing plan and gives us measurable checkpoints that go well beyond the number on the scale
Cancer Res 1989
Subsequently, cGAMP is detected by the STING protein on the endoplasmic reticulum (ER) membrane, and activates it through conformational changes, thereby triggering the NF-B and interferon regulatory factor 3 (IRF3) signaling pathways and promoting the secretion of pro-inflammatory cytokines and type I interferons
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