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This rigorous evaluation process, spanning nearly a decade from initial concept to regulatory approval, reflects the comprehensive approach required for novel diabetes therapeutics

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At the tirzepatide 15mg/weekly dose, the most commonly reported side effects included: Nausea: 24.08% Diarrhea: 20.79% Belching: 16.42% Bloating: 16.29% Gut discomfort: 14.86% Vomiting: 13.98% Constipation: 8.86% Indigestion: 8.52% Abdominal pain: 7.57% Hypersensitivity reactions affected 2-4% of participants

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The day after discontinuing WEGOVY tablets 25 mg once daily, initiate WEGOVY 2.4 mg subcutaneous injection once weekly

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