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Phase III results for retatrutide are set to be released later in 2025 and in early 2026, but an earlier phase II trial recorded between a 7.2% and 17.5% reduction in body weight after 24 weeks, depending on the dose (7.2% on 1mg, 17.5% on 12mg), and up to a 24.2% reduction in body weight after 48 weeks for those on 12mg (-8.7% change for those on 1mg) 8
This study also demonstrated that MAbs can be used not only as drug delivery platforms that increase the penetration of drugs through the BBB but also as individual therapeutic agents [189]
Understanding how these averages were reached can make it easier to interpret your own resultsand avoid assuming something is wrong when your experience doesnt match a headline number
doi: 10.1111/j.1753-4887.2006.tb00202.x 36 MehedintMGCraciunescuCNZeiselSH
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