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Effect of l-carnitine on cardiotoxicity and apoptosis induced by imatinib through [PMID: 33844974] Laboratory literature summary: Effect of l-carnitine on cardiotoxicity and apoptosis induced by imatinib through PDGF/ PPAR /MAPK pathways
Primary Carnitine Deficiency Syndromes Two distinct carnitine deficiency states have been reported although a rigid distinction between "primary" and "secondary" carnitine deficiency is difficult to establish in some cases [10]
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Similarly, IRE1 dysregulation has been observed in tauopathies, PrD, and HD, highlighting its role in neurotoxicity, whereas ATF6 dysfunction exacerbates protein aggregation and has been linked to FTD and tauopathies
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