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Polioencephalomalacia More commonly called goat polio or simply thiamine deficiency, polioencephalomalacia is a neurological disease characterized by brain swelling and tissue death the word literally means softening of the brain. Ruminants harbor beneficial bacteria and protozoa that produce Vitamin B12 (cobalamin) and Vitamin B1 (thiamine) under normal environmental conditions
Many patients or their family members are capable of giving IM injections after appropriate training
It is fundamentally different from immunosuppression because it targets only the specific immune response against myelin, leaving the rest of the immune system intact
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