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The method of claim 1 , wherein PT-141 is administered no later than about 30 minutes prior to the end of the average half-life of the PDE-5 inhibitor

Inhibition of DPP 4 activity in humans establishes its in vivo role in CXCL 10 post-translational modification: Prospective placebo-controlled clinical studies

And critically, it needs to be effective at very low doses because even with skin-penetration enhancers, you're rarely getting more than a few milligrams across in 24 hours

Higher Bioavailability Injections can provide higher bioavailability, meaning a greater proportion of the vitamin or mineral is available for the body to use