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Administered as a once-weekly subcutaneous injection, it works by mimicking the action of naturally occurring GLP-1, a hormone released by the intestine in response to food intake

Therefore, this study provided the first evidence of functional GLP-1R expression in human iTreg cells, and suggested that GLP-1R might play a key role in the anti-inflammatory effects attributed to GLP-1RA

doi: 10.2337/cd19-0079 26 NauckMAStewartMWPerkinsCJones-LeoneAYangFPerryCet al

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