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FDA advisory committees and review divisions retain authority to question whether trial populations, wherever they were enrolled globally, support a claim about a US patient population, and sponsors running geographically concentrated trials outside the United States should expect that scrutiny to continue regardless of the DAP guidance's administrative status
A study comparing adherence between people with T2D that use insulin and those using GLP-1s found that insulin users had an adherence level of around 90% compared with around 74% for those using GLP-1s (both oral and injectable versions).9 For those using GLP-1s for weight loss, injections are a choice
Aftercare and what to expect Most people can return to normal activities straight away
It is often described as a triple agonist because it targets GLP-1, GIP, and glucagon pathways
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