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After recording routine oxygen consumption rate, sequential injections of metabolic inhibitors and uncouplers were performed: 0.25 M oligomycin (OLIG), 0.753.5 M carbonylcyanide-p-trifluoromethoxyphenylhydrazone (FCCP), and 0.25 M rotenone (ROT), to record respiratory rates representing proton leak-driven respiration (LEAK), maximal capacity of the electron-transport system (ETS), and non-mitochondrial residual oxygen consumption (ROX) (Fig
Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice
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