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GSH can also serve as a substrate for S-glutathionylation of proteins in the presence of small redox enzyme glutaredoxins (GRX), which also utilizes GSH as a cofactor ( Figure 1 )
Why an imbalance between Phase I and II matters: Phase I detoxification processes often make a lipophilic (lipid-soluble) substance more hydrophilic for increased solubility
Cell 185 , 24782494.e2428 (2022)
Plain-English explanation: Epithalon is a laboratory-made chain of four amino acids
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