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There are no reported risks associated with large doses of B12, since the vitamin is water soluble and excess amounts are flushed out of the system
Researchers became interested in the combination after observing that glutathione levels tend to decline with age while oxidative stress, inflammation, and mitochondrial dysfunction increase.59 The idea is that providing both cysteine and glycine may help the body rebuild glutathione more efficiently than either nutrient alone
Redox compartmentalization in eukaryotic cells
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