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Blood 134 , 395406 (2019)

This method allows for direct absorption into the bloodstream, bypassing the digestive system

Baldi S, Dinu M, Pagliai G, Colombini B, Di Gloria L, Curini L et al (2022) Effect of ancient wheat pasta on gut microbiota composition and bacteria-derived metabolites: a randomized controlled trial

Patients can present with the following signs & symptoms: CNS (areflexia, asthenia, ataxia, blurred vision, disorientation, dizziness, drowsiness, hyporeflexia, slurred speedh, somnolence, staggering, tiredness, coma) Cardiovascular (initial hypertension, followed by long-lasting hypotension , bradycardia , premature ventricular beats) the peripheral actions of xylazine cause an initial increase in blood pressure, followed by central effects that result in a long-lasting hypotensive effect, accompanied by bradycardia and reduced cardiac output (Hoffman et al, 2001)