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Pharmacokinetic interactions (how drugs affect each other's absorption, distribution, metabolism, or elimination) between Ozempic and most antidepressants are generally considered minimal

Supporting that idea, one preclinical study tested SNAC-based oral delivery of a dual GIP/GLP-1 peptidesimilar in class to tirzepatide, though not tirzepatide itselfand found that bioavailability remained low and highly variable in animal models

Using expired or improperly stored medication may reduce weight-management efficacy or, in rare cases, introduce sterility concerns if contamination occurred

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